Health
Racial Disparities in Breast Cancer
Jasmine Souers was 25 when she noticed a discharge from her nipples. Concerned, she went to get it checked out. At first, her doctors dismissed the possibility of breast cancer, saying, she’s “too young.”
She didn’t feel any lumps. A mammogram — a type of breast X-ray — and an ultrasound — a scan that uses sound waves — didn’t show any signs of cancer. Her doctor thought the discharge was caused by an infection and gave her antibiotics.
Six months later, Souers went to an OB/GYN. The Jacksonville, FL, native was 2 years into her marriage and was considering starting a family. But she was adamant about the discharge, which at this point, had become bloody.
“I said ‘I really think we need to check this out before we go any further,'” Souers says. After the doctor referred her to a specialist, a breast MRI confirmed multiple tumors and stage I breast cancer.
“It was a chaotic time,” Souers recalls.
Souers is one of the many Black women who are under the age of 45 and disproportionately more likely to get breast cancer in the U.S.
“There are a number of disparities around breast cancer that are really sobering in terms of why outcomes for black women are significantly poorer than for White women,” says Dorraya El-Ashry, PhD, chief scientific officer at the Breast Cancer Research Foundation.
Breast cancer is the second leading cause of death among women in the U.S. It affects 1 in 8 women, and 1 in 39 women die from this disease.
Breast cancer numbers have begun to fall in the last few years due to better treatments and early detection. But they’re still high for Black women compared with White women.
Research shows that White women are more likely to be diagnosed with breast cancer than any other racial or ethnic group. But the death rate for Black women is 40% higher.
Black women are also more likely to get cancer earlier in life and twice as likely to be diagnosed with aggressive forms of cancer like triple-negative breast cancer.
Black women are also more likely to be diagnosed with late-stage breast cancer than White women.
Research shows that poverty, social injustice, and structural racism may play a large role in the different ways breast cancer affects Black and White women.
Regardless of race, women with low incomes are less likely to have regular health screenings, treatments, and follow-ups. Research shows that more women of color, especially Hispanic and Black women, live in poverty than White women.
Lower income can affect access to health insurance and good quality health care. When you’re struggling financially, you also might not be able to keep up with a healthy diet and lifestyle. Tobacco use and obesity, for example, can raise your chances of getting breast cancer.
El-Ashry says genes may play a role, too. She says that research shows that Black women are more likely than whites to have BRCA1 and BRCA2 mutations — changes in genes that make you more likely to get breast cancer.
Experts say Black Americans also tend to have a higher level of mistrust in medical authorities. This usually stems from a legacy of the discrimination and racism the community has faced in the past.
Finding a community that you can relate to is sometimes an issue for Black women with breast cancer. Souers found this to be true when she was seeking information about surgery.
After her breast cancer diagnosis, Souers says she was looking for the “path of least resistance” to make sure the cancer wouldn’t come back. She chose a bilateral mastectomy. In that procedure, a surgeon removes both breasts.
Before the surgery, Souers was curious about how her breasts would look afterwards. When she ran a simple Google search to see what Black women with bilateral mastectomy look like, mostly images of White women turned up.
“My antennas go up. So, are Black women not getting double mastectomies? Are they having bad doctors? Are my doctors asking me to do something other Black women aren’t doing? All of this made me anxious,” Souers says.
Marissa Thomas ofTacoma, WA, had a similar experience after she was diagnosed with stage II breast cancer at age 41 in November 2015. The following year, she had to go through “the whole gamut of treatment” — a lumpectomy (removal of part of breast), chemotherapy, radiation, and two breast reconstruction surgeries.
During that trying time, Thomas says she “didn’t see anybody that … looked like me that was going through treatment. I knew that they were out there, but just trying to connect with them and have an online support group — there just wasn’t any out there,” Thomas says.
But thanks to the internet, Thomas and Souers connected with each other online on Instagram. Later, the two met in-person at a meeting, where they realized they had a lot in common. Sensing a lack of community for women of color with breast cancer, the two women co-founded a group called For the Breast of Us.
The group’s mission, Thomas says, is to uplift and empower women of color with breast cancer with the tools necessary to advocate for themselves as they navigate the bumpy medical journey. Today, the group’s private Facebook page has over 700 members who look to the community for advocacy, support, and empowerment.
One of the core missions at For the Breast of Us, Thomas says, is “wanting to know why a lot of women of color aren’t part of clinical trials” when it comes to breast cancer.
Clinical trials are studies that let scientists learn about how well new treatments work. It’s another area where Black women’s representation is sharply lower than White women.
“They [Black women] have fewer opportunities to participate in clinical trials, and they participate less in clinical research and other kinds of research,” El-Ashry says.
Black people make up only 6.2% of participants of clinical trials, Asians 3.3%, Hispanics 2.2%, and Native Americans 0.1%.
“I think like everything else, it’s a complex picture. In clinical trials themselves, if people have poor health because of co-morbid [underlying] conditions, they’re less likely to be enrolled in a clinical trial. And since there is a bigger proportion of that in the Black breast cancer community, that can lead to that,” El-Ashry says.
El-Ashry says it’s also an issue of awareness. “Awareness of the importance of clinical trials and even the opportunity to be, for example, at the scene, at a place that’s involved in clinical trials. So, it’s about the level of access and representation.”
Screening refers to checking for breast cancer when you don’t have a lump. This is because cancers can be so tiny that you don’t feel them. A diagnostic mammogram is a mammogram you get to look at a breast lump or other specific concern.
Medical groups don’t all agree on when to start getting screening mammograms. You may want to talk with your doctor about what’s best for you.
The U.S. Preventive Services Task Force (USPSTF) has updated its guidelines to recommend that women start getting annual screening mammograms at age 40. But other organizations have slightly different recommendations. For instance, the American Cancer Society’s guidelines say women of average risk for breast cancer between 45 and 54 should get a mammogram every year to check for breast cancer. Women 40 to 44 have the option to have a scan every 2 years while those older than 55 can choose to continue the scans each year or opt for every 2 years.
If you have family history or genetics that increase your risk of breast cancer, talk to your doctor about getting an MRI along with the mammogram. Since women of color are diagnosed with more aggressive cancer at later stages, El-Ashry says researchers are checking to see if there are benefits to modifying the screening guidelines. One new study wants to find out if screening guidelines should focus more on whether people have specific risks for breast cancer, rather than your age.
“I think that is definitely an area that the field is moving into with the idea that if we could understand your risk, then we would come up with guidelines to go with that risk,” El-Ashry says.
Things that raise your chances of getting breast cancer include poor nutrition, drinking alcohol, obesity, tobacco use, family history, and gene mutations.
Thomas says doctors can help close the racial gap in breast cancer care by paying close attention to the needs of women of color.
“Listen to your patients, especially your Black and brown patients,” Thomas says. “I don’t think a lot of providers are fully listening to their patients. They’re not aware of where they may be falling short.”
Thomas also says doctors could also consider connecting their patients with other patient advocates or patient navigators within their community. This is so that they have somebody that they could fall back on in case they just can’t relate to their medical providers or they just want somebody to break it down to them in layman’s terms.”
“One thing I want to say to the medical community is checking their biases at the door. We all come with biases, but make sure that you’re not taking that into the care of the patients that you’re serving,” Thomas says.
Souers says it also takes allies in the breast cancer community who don’t identify as women of color to use their privilege and platform to call out the injustices happening to women of color with breast cancer. Through their advocacy effort, Souers and Thomas created an accomplice guide — a list of dos and don’ts to elevate and amplify the narratives of women of color in the community and share access to resources to care and information that they may otherwise not have.
Over the last 30 years, research has helped lower the death rate in breast cancer by about 40%. But this has largely benefitted white women in the community.
“What we need is to be able to have that affect this gap in disparities here, and so that will come from research and that will come from deeper investments in disparities research, and again, that takes money and will,” El-Ashry says.
The racial gap is devastating communities of color. Souers says it’s about doing everything to at least level the playing field.
“At some point it’s like, what are we going to do? Women are dying. We can’t tell you how many friends we’ve lost in the last couple of months. Women are dying. They deserve better. Their parents, their children, their partners — they deserve better. And we need to have some conversations to actually put a plan in place that we can make it so that if we are dying, at least we are dying at the same rate. Not far out exceeding everyone else,” Souers says.
May 10, 2024 – When we’re young, we take our macula for granted. At the center of our retina – the deepest layer of the eye that’s chock-full of photoreceptors and that confers color to our world – the macula is like a high-resolution camera. As light hits our eyes, the retina’s macula recasts our world in a bloom of color with astoundingly high visual sharpness.
But as you age, your vision dulls. What once stood out sharply becomes foggy, like condensation on a windowpane. After some time, a coal-black smudge or cloudy circular area begins to affect your central vision.
This effective blind spot widens over time if left untreated. What remains is a “macular hole” in the center of your retina.
This unfortunate series of events marks the advanced stage of age-related macular degeneration, a dangerous retinal disease that affects about 20 million people in the U.S., and nearly 200 million people worldwide.
And it’s not getting better. Estimates are that by 2040, the disease may affect nearly 300 million people worldwide. We are very limited in our ability to treat or prevent it. Read on for what to know.
First, What Causes Age-Related Macular Degeneration?
AMD’s causes are varied, and whether it will affect you is mostly determined by age and genetics, said Marco Alejandro Gonzalez, MD, an ophthalmologist and vitreoretinal specialist in Delray Beach, FL.
Because of the different cocktails that we have in terms of our genetic makeup, some people’s photoreceptor cells in the macula “basically start to shut down,” he said.
AMD’s development involves over 30 genes, and if you have a first-degree relative – parent, sibling, child – who has the disease, you’re three times more likely to get it, too.
Gonzalez explained how the expected rise to 300 million cases by 2040 is due mostly to improved diagnostic tools, along with the fact that the world is getting older and living longer. (Usually, an optometrist can detect signs of AMD during a routine eye exam.)
Eye experts still struggle to stop AMD’s most harmful sign – the cause of those muddy, milky, or even coal-colored circles in your central vision: geographic atrophy.
Geographic atrophy can occur in either of the two forms of age-related AMD: “dry” AMD and “wet” AMD.
Nearly every case of AMD begins as the dry kind, affecting 80% to 90% of AMD patients.
Retinal disease expert Tiarnán Keenan, MD, PhD, offered a vivid image of geographic atrophy for those who have dry AMD.
“As time passes, the circular patches of GA expand like a brushfire, taking more and more vision with it, often to the point of legal blindness,” he said.
A researcher in the Division of Epidemiology and Clinical Applications at the National Eye Institute, Keenan recently led a study that tested the efficacy of the antibiotic minocycline in slowing geographic atrophy expansion in dry AMD. The study operated on the grounds that the body’s immune system could be at play in developing the disease.
When your body’s immune system is overactive, microglial cells (central nervous system immune cells) can get into the sub-retinal space and possibly eat away at the macula and its sensitive photoreceptors.
Though minocycline had been shown to reduce inflammation and microglial activity in the eye in diabetic retinopathy, it didn’t slow the expansion of geographic atrophy or vision loss in patients with dry AMD during Keenan’s study.
When asked if microglial activity could have very little to do with the atrophy expansion, Keenan said it’s something to consider: “Maybe microglia are just there as bystanders clearing up the debris … so inhibiting them is less likely to slow down progression.”
In future drug trials, “maybe it’s possible the minocycline or another approach to target microglia would be helpful, but it would be needed in combination with some other therapy and be ineffective by itself,” he said.
Two Sides of the Same Disease
In dry AMD, Gonzalez compares macular degeneration to the loss of pixels on a screen. “Some of those pixels burn out … and that’s the way you lose vision classically in the dry form.”
Wet AMD is a more progressive form of the disease. It causes abrupt vision loss due to abnormal blood vessel growth.
“If you don’t treat wet AMD quickly, it’s game over,” warned Gonzalez. “Wet macular degeneration is the quicker process of vision loss because these blood vessels wreak havoc.” These new blood vessels bleed, causing fluid to build in the macula, which ultimately leads to scarring.
Gonzalez shed light on why wet AMD develops. “The wet form, for some reason, is the body’s last-ditch effort to try to kind of ‘help’ a dying macula. … When these blood vessels start to grow under the retina, they quickly destroy the architecture of the macula.”
Stopping the Bleeding in Wet AMD
Though wet AMD is rarer, it’s more treatable than dry AMD. Signs and symptoms can be eased with various therapies injected into the eye.
Putting it simply, Gonzalez said these therapies to treat wet AMD “all basically do the same thing. They make these new blood vessels regress temporarily before they cause damage to the macula.”
The injected medication clears away those blood vessels and restores the architecture of the macula. People can recover some vision in this way, but it’s only a temporary tune-up, and shots must be given as often as once a month.
“Degeneration of the cells is still the main problem. You’re not stopping that. But degeneration itself is a lot slower than actual vision loss associated with these blood vessels.”
The Struggle in Developing New Treatments
According to Keenan, “nobody has been able to stop geographic atrophy from happening” in either form of AMD. “So, that’s the main work in the field with trials.”
In December 2023, the FDA approved two new drugs: Syfovre and Izervay, both of which only slow geographic atrophy. Degeneration still happens, regardless.
Keenan explained how these two new drugs are “complement inhibitors … given by injection into the eye once a month or so.”
“Complement” refers to the body’s complement pathway, a trigger that activates a cascade of proteins in enhancing immune response.
Clinical trials showed Syfovre slowing the rate of geographic atrophy by up to 22% over 2 years, and Izervay up to 14% over 1 year.
Though these drugs are a new weapon against this troublesome affliction, they aren’t without their complications.
“Anytime you give an injection in the eye, there’s always the risk of an infection because you’re introducing something from the outside. So that’s the biggest risk,” explained Gonzalez.
An infection is uncommon, but potentially devastating, as you can lose your eye altogether. There’s also the chance of a damaging reaction to the shot.
“You have to pick and choose your patients,” said Gonzalez. “Not everybody is a good candidate for those new shots … and the patient is never going to see better. … It’s a harder sell than the ones for wet AMD.”
A Common Protective Measure
Keenan and Gonzalez both have a fair degree of confidence in reducing the risk of AMD with vitamin therapy.
As a bit of background on how vitamins were found to act as a sort of preventive measure, Gonzalez said, “In the early and late ‘90s, there were series of studies which were called the age-related eye disease studies.” These are now referred to as AREDS 1 and AREDS 2.
Researchers proved that a certain cocktail of vitamins slowed down degeneration. The most is a combo of antioxidants: vitamins C and E and lutein and zeaxanthin, all of which are in the AREDS 2 formula.
People who took these vitamins had a lower chance of losing their vision over the next 2 to 5 years. “[The combo] seems to be complementary and additive … with a combined treatment effect of 55% to 60%, an excellent safety record, and very low cost,” Keenan said.
Gonzalez recommends the AREDS 2 formula of vitamins to every patient of his. “It’s such an easy thing to take, and the downside is minimal.”
Unfortunately, if your genes make you more likely to have the condition, a change in diet or vitamin use could have no effect.
Dire? Possibly. But not all is lost in this fight.
Vigilance with AMD and What to Do Next if You’re Diagnosed
Gonzalez is adamant in educating his patients before time has run out on treating AMD. Recognition is key. “The most common reason a lot of these people get to me ‘too late’ is they don’t realize there’s a problem.”
He explained a typical scenario: “Let’s say you have macular degeneration in both eyes at different stages. One of your eyes starts developing wet macular degeneration … so the better eye takes over and you may not notice there’s a problem.”
Even after a patient is diagnosed with AMD, they usually see a specialist only twice a year. Gonzalez often tells his patients to cover one of their eyes to make sure their vision is intact in both eyes. “You’ll be able to pick up on subtle differences” in each eye, he said.
This type of self-care and vigilance can be the difference between successfully living with and treating the disease for the rest of your life, and trying to get help when it’s simply too late.
For wet AMD, as mentioned before, a round of injections is basically what everyone does. Without quick, invasive treatment, the point of no return approaches rapidly.
May 16, 2024 – Multiple U.S. agencies are working to contain the recent bird flu outbreak among cattle to prevent further spread to humans (beyond one case reported in early April) and use what we learned before, during, and after the COVID-19 pandemic to keep farm workers and the general public safe.
Fingers crossed, the bird flu will be contained and peter out. Or the outbreak could continue to spread among dairy cattle and other animals, threatening the health and livelihoods of farmers and others who work with livestock.
Or the virus could change in a way that makes it easier to infect and spread among people. If this happens, the worst-case scenario could be a new influenza pandemic.
With so many unknowns, WebMD brought together experts from four federal agencies to talk prevention, monitoring, and what the “what ifs” of bird flu might look like.
Communication with the public “about what we know, what we don’t know, and ways you and your family can stay safe is a priority for us at CDC,” said Nirav D. Shah, MD, JD, the CDC’s principal deputy director. “We at the federal level are responding, and we want the public to be following along.”
People should consult the websites for the CDC, FDA, U.S. Department of Agriculture (USDA), and the Administration for Strategic Preparedness and Response (ASPR) for updates.
It is essential to not only stay informed, but to seek trusted sources of information, Shah said during “Bird Flu 2024 – What You Need to Know,” an online briefing jointly sponsored by the CDC and WebMD.
An ‘Experimental Hamburger’
If one take-home message emerged from the event, it was that the threat to the general public remains low.
The retail milk supply is safe, although consuming raw or unpasteurized milk is not recommended. “While commercial milk supply is safe, we strongly advise against drinking raw milk,” said Donald A. Prater, DVM, acting director for the FDA’s Center for Food Safety and Applied Nutrition.
As for other foods, thoroughly cooked eggs are less risky than raw eggs, and the nation’s beef supply remains free of the virus as well.
For years, federal inspectors have purchased and tested meat at retail stores, said Eric Deeble, DVM, USDA deputy assistant secretary for the Office of Congressional Relations. So far, H5N1, the virus behind bird flu, has not been detected in beef.
The USDA took testing a step further and recently cooked ground beef from dairy cows in their lab. Using what Deeble described as an “experimental hamburger,” the agency showed cooking beef to 165 F or higher kills the virus if it ever becomes necessary.
The federal government now requires all cattle be tested and be free of bird flu virus before crossing any state lines. The government is also reimbursing farmers for veterinary care and loss of business related to the outbreak, and supply personal protective equipment (PPE) like gloves, masks, and face shields to workers.
Vaccination Not Recommended Now
Federal scientists know enough about H5N1 virus to create vaccines against it quickly if the need arises. It’s more about planning ahead at this point. “Vaccines are not part of our response right now,” said David Boucher, PhD, director of infectious diseases preparedness and response at the Administration for Strategic Preparedness and Response.
If the virus changes and becomes a bigger threat to people, “we have the building blocks to produce a vaccine,” Boucher added.
An event attendee asked if the seasonal flu shot offers any protection. “Unfortunately, the flu shot you got last year does not provide great protection from the avian flu,” Shah responded. “It might do a little bit … but that is the vaccine for seasonal flu. This is something more novel.”
Treatments Stockpiled and Ready
Antiviral medications, which if given early in the course of bird flu infection could shorten the severity or duration of illness, are available now, Shah said. The dairy farmer who was infected with bird flu earlier this year responded to oseltamivir (Tamiflu) treatment, for example.
When it comes to bird flu symptoms, the fact that the only infected person reported so far this year developed pink eye, also known as conjunctivitis, is interesting, Shah said. Officials would have expected to see more typical seasonal flu symptoms, he added.
“Influenza is not a new virus,” Boucher said. “With this strain of influenza, we are not seeing any genetic markers associated with resistance to antivirals. That means the antivirals we take for seasonal influenza would also be available if needed to treat H5N1.”
ASPR has stockpiled Tamiflu and three other antivirals. “We do have tens of millions of courses that can be distributed around the country if we need them,” he added.
“Influenza is an enemy we know well,” Boucher said. That is why “we have antivirals ready to go now and many types of PPE.”
Science in Action
The feds intend to stay on the case. They will continue to monitor emergency department visits, lab test orders, and wastewater samples for any changes suggesting a human pandemic risk is growing.
“While we’ve learned a great deal, there are still many things we do not know,” Deeble said.
Shah added, “As in any outbreak, this is an evolving situation and things can change. What you are seeing now is science in action.”
For the latest updates on bird flu in the United States, visit the CDC’s H5N1 Bird Flu: Current Situation Summary website.
May 16, 2024 – Multiple U.S. agencies are working to contain the recent bird flu outbreak among cattle to prevent further spread to humans (beyond one case reported in early April) and use what we learned before, during, and after the COVID-19 pandemic to keep farm workers and the general public safe.
Fingers crossed, the bird flu will be contained and peter out. Or the outbreak could continue to spread among dairy cattle and other animals, threatening the health and livelihoods of farmers and others who work with livestock.
Or the virus could change in a way that makes it easier to infect and spread among people. If this happens, the worst-case scenario could be a new influenza pandemic.
With so many unknowns, WebMD brought together experts from four federal agencies to talk prevention, monitoring, and what the “what ifs” of bird flu might look like.
Communication with the public “about what we know, what we don’t know, and ways you and your family can stay safe is a priority for us at CDC,” said Nirav D. Shah, MD, JD, the CDC’s principal deputy director. “We at the federal level are responding, and we want the public to be following along.”
People should consult the websites for the CDC, FDA, U.S. Department of Agriculture (USDA), and the Administration for Strategic Preparedness and Response (ASPR) for updates.
It is essential to not only stay informed, but to seek trusted sources of information, Shah said during “Bird Flu 2024 – What You Need to Know,” an online briefing jointly sponsored by the CDC and WebMD.
An ‘Experimental Hamburger’
If one take-home message emerged from the event, it was that the threat to the general public remains low.
The retail milk supply is safe, although consuming raw or unpasteurized milk is not recommended. “While commercial milk supply is safe, we strongly advise against drinking raw milk,” said Donald A. Prater, DVM, acting director for the FDA’s Center for Food Safety and Applied Nutrition.
As for other foods, thoroughly cooked eggs are less risky than raw eggs, and the nation’s beef supply remains free of the virus as well.
For years, federal inspectors have purchased and tested meat at retail stores, said Eric Deeble, DVM, USDA deputy assistant secretary for the Office of Congressional Relations. So far, H5N1, the virus behind bird flu, has not been detected in beef.
The USDA took testing a step further and recently cooked ground beef from dairy cows in their lab. Using what Deeble described as an “experimental hamburger,” the agency showed cooking beef to 165 F or higher kills the virus if it ever becomes necessary.
The federal government now requires all cattle be tested and be free of bird flu virus before crossing any state lines. The government is also reimbursing farmers for veterinary care and loss of business related to the outbreak, and supply personal protective equipment (PPE) like gloves, masks, and face shields to workers.
Vaccination Not Recommended Now
Federal scientists know enough about H5N1 virus to create vaccines against it quickly if the need arises. It’s more about planning ahead at this point. “Vaccines are not part of our response right now,” said David Boucher, PhD, director of infectious diseases preparedness and response at the Administration for Strategic Preparedness and Response.
If the virus changes and becomes a bigger threat to people, “we have the building blocks to produce a vaccine,” Boucher added.
An event attendee asked if the seasonal flu shot offers any protection. “Unfortunately, the flu shot you got last year does not provide great protection from the avian flu,” Shah responded. “It might do a little bit … but that is the vaccine for seasonal flu. This is something more novel.”
Treatments Stockpiled and Ready
Antiviral medications, which if given early in the course of bird flu infection could shorten the severity or duration of illness, are available now, Shah said. The dairy farmer who was infected with bird flu earlier this year responded to oseltamivir (Tamiflu) treatment, for example.
When it comes to bird flu symptoms, the fact that the only infected person reported so far this year developed pink eye, also known as conjunctivitis, is interesting, Shah said. Officials would have expected to see more typical seasonal flu symptoms, he added.
“Influenza is not a new virus,” Boucher said. “With this strain of influenza, we are not seeing any genetic markers associated with resistance to antivirals. That means the antivirals we take for seasonal influenza would also be available if needed to treat H5N1.”
ASPR has stockpiled Tamiflu and three other antivirals. “We do have tens of millions of courses that can be distributed around the country if we need them,” he added.
“Influenza is an enemy we know well,” Boucher said. That is why “we have antivirals ready to go now and many types of PPE.”
Science in Action
The feds intend to stay on the case. They will continue to monitor emergency department visits, lab test orders, and wastewater samples for any changes suggesting a human pandemic risk is growing.
“While we’ve learned a great deal, there are still many things we do not know,” Deeble said.
Shah added, “As in any outbreak, this is an evolving situation and things can change. What you are seeing now is science in action.”
For the latest updates on bird flu in the United States, visit the CDC’s H5N1 Bird Flu: Current Situation Summary website.
LG confirms game-changing upgrade for these TVs – is your model on the list?
Unscripted moment in Full Metal Jacket led to iconic scene | Films | Entertainment
‘Best movie of all time’ is now streaming on Netflix | Films | Entertainment
Education3 weeks agoCruise ship expert urges passengers to bring key magnetic items on board | Cruise | Travel
- Education3 weeks ago
People are just realising what ‘kiss of death’ code means on boarding pass | Travel News | Travel
- Video3 weeks ago
Putin Says He’s Ready to Discuss Oil, Energy Issues With Trump
- Movies2 weeks ago
Who Is Lawyer C Sankaran Nair And Why His Story Needs To Be Told
- Entertainment2 weeks ago
Save money on Last of Us Complete and get spare PlayStation credit with discount deal | Gaming | Entertainment
- Sports2 weeks ago
Jude Bellingham ‘in training bust-up’ and separated from team-mate | Football | Sport
- Sports2 weeks ago
Bahrain Grand Prix qualifying results changed as Mercedes slapped with brutal penalties | F1 | Sport
- Sports1 week ago
Arsenal player ratings vs Real Madrid: 10/10 given as Gunners progress to semi-finals | Football | Sport
